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BDBM50378545 CHEMBL585545

SMILES: Cc1ccc(cc1)C(=O)CN1C(=O)SC(=Cc2ccc(o2)-c2ccc(Cl)cc2)C1=O

InChI Key: InChIKey=CGYYIFBEGMCBSD-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50378545   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Integrin alpha M/beta-2


(Homo sapiens (Human))
BDBM50378545
PNG
(CHEMBL585545)
Show SMILES Cc1ccc(cc1)C(=O)CN1C(=O)SC(=Cc2ccc(o2)-c2ccc(Cl)cc2)C1=O |w:15.16|
Show InChI InChI=1S/C23H16ClNO4S/c1-14-2-4-15(5-3-14)19(26)13-25-22(27)21(30-23(25)28)12-18-10-11-20(29-18)16-6-8-17(24)9-7-16/h2-12H,13H2,1H3
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KEGG

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>5.00E+4n/an/an/an/a



Department of Medicine and University of Miami

Curated by ChEMBL


Assay Description
Agonist activity at CD11b/CD18 expressed in K562 cells assessed as increase in cell adhesion to fibrinogen


Bioorg Med Chem Lett 19: 6902-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.077
BindingDB Entry DOI: 10.7270/Q2NS0VV0
More data for this
Ligand-Target Pair