null

SMILES: [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@@H]-1-[#7]-[#6](=O)-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#8])=O)-[#6](=O)-[#7]-[#6@H](-[#6]-c2ccccc2)-[#6]-[#7]-[#6]-1=O

InChI Key: InChIKey=JBCUWZUACLSOTF-PMPSAXMXSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50378570   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha-5/beta-1 (Homo sapiens (Human))	BDBM50378570 (CHEMBL572085) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@@H]-1-[#7]-[#6](=O)-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#8])=O)-[#6](=O)-[#7]-[#6@H](-[#6]-c2ccccc2)-[#6]-[#7]-[#6]-1=O |r| Show InChI InChI=1S/C22H31N7O6/c23-22(24)25-8-4-7-15-20(34)26-12-14(9-13-5-2-1-3-6-13)27-21(35)16(10-19(32)33)29-18(31)11-17(30)28-15/h1-3,5-6,14-16H,4,7-12H2,(H,26,34)(H,27,35)(H,28,30)(H,29,31)(H,32,33)(H4,23,24,25)/t14-,15+,16+/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Bologna Curated by ChEMBL					Assay Description Inhibition of alpha5beta1 integrin-mediated cell adhesion in human K562 cells on fibronectin coated plate after 30 mins				J Med Chem 53: 106-18 (2010) Article DOI: 10.1021/jm9013532 BindingDB Entry DOI: 10.7270/Q2G161S9
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50378570 (CHEMBL572085) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@@H]-1-[#7]-[#6](=O)-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#8])=O)-[#6](=O)-[#7]-[#6@H](-[#6]-c2ccccc2)-[#6]-[#7]-[#6]-1=O |r| Show InChI InChI=1S/C22H31N7O6/c23-22(24)25-8-4-7-15-20(34)26-12-14(9-13-5-2-1-3-6-13)27-21(35)16(10-19(32)33)29-18(31)11-17(30)28-15/h1-3,5-6,14-16H,4,7-12H2,(H,26,34)(H,27,35)(H,28,30)(H,29,31)(H,32,33)(H4,23,24,25)/t14-,15+,16+/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Bologna Curated by ChEMBL					Assay Description Inhibition of alphavbeta3 integrin-mediated cell adhesion in human SK-MEL-24 cells on fibronectin coated plate after 30 mins				J Med Chem 53: 106-18 (2010) Article DOI: 10.1021/jm9013532 BindingDB Entry DOI: 10.7270/Q2G161S9
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50378570 (CHEMBL572085) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@@H]-1-[#7]-[#6](=O)-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#8])=O)-[#6](=O)-[#7]-[#6@H](-[#6]-c2ccccc2)-[#6]-[#7]-[#6]-1=O |r| Show InChI InChI=1S/C22H31N7O6/c23-22(24)25-8-4-7-15-20(34)26-12-14(9-13-5-2-1-3-6-13)27-21(35)16(10-19(32)33)29-18(31)11-17(30)28-15/h1-3,5-6,14-16H,4,7-12H2,(H,26,34)(H,27,35)(H,28,30)(H,29,31)(H,32,33)(H4,23,24,25)/t14-,15+,16+/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Bologna Curated by ChEMBL					Assay Description Inhibition of alphavbeta3 integrin-mediated cell adhesion in HUVEC on vitronectin coated plate after 30 mins				J Med Chem 53: 106-18 (2010) Article DOI: 10.1021/jm9013532 BindingDB Entry DOI: 10.7270/Q2G161S9
					More data for this Ligand-Target Pair