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BDBM50378688 CHEMBL599562

SMILES: Cc1cn([C@@H]2CN(C[C@H]2O)C(=O)P(O)(O)=O)c(=O)[nH]c1=O

InChI Key: InChIKey=CFDPBOPUGKGHEZ-RNFRBKRXSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50378688   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Thymidine phosphorylase


(Rattus norvegicus)
BDBM50378688
PNG
(CHEMBL599562)
Show SMILES Cc1cn([C@@H]2CN(C[C@H]2O)C(=O)P(O)(O)=O)c(=O)[nH]c1=O |r|
Show InChI InChI=1S/C10H14N3O7P/c1-5-2-13(9(16)11-8(5)15)6-3-12(4-7(6)14)10(17)21(18,19)20/h2,6-7,14H,3-4H2,1H3,(H,11,15,16)(H2,18,19,20)/t6-,7-/m1/s1
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Similars

Article
PubMed
n/an/a 220n/an/an/an/an/an/a



Academy of Sciences of the Czech Republic

Curated by ChEMBL


Assay Description
Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphate


Bioorg Med Chem Lett 20: 862-5 (2010)


Article DOI: 10.1016/j.bmcl.2009.12.081
BindingDB Entry DOI: 10.7270/Q2930V4K
More data for this
Ligand-Target Pair