BDBM50378691 CHEMBL609919

SMILES: Cc1cn([C@@H]2CN(C[C@@H]2O)C(=S)P(O)(O)=O)c(=O)[nH]c1=O

InChI Key: InChIKey=VNDWJLZGVZKKNV-RQJHMYQMSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50378691   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thymidine phosphorylase (Rattus norvegicus)	BDBM50378691 (CHEMBL609919) Show SMILES Cc1cn([C@@H]2CN(C[C@@H]2O)C(=S)P(O)(O)=O)c(=O)[nH]c1=O |r| Show InChI InChI=1S/C10H14N3O6PS/c1-5-2-13(9(16)11-8(5)15)6-3-12(4-7(6)14)10(21)20(17,18)19/h2,6-7,14H,3-4H2,1H3,(H,11,15,16)(H2,17,18,19)/t6-,7+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphate				Bioorg Med Chem Lett 20: 862-5 (2010) Article DOI: 10.1016/j.bmcl.2009.12.081 BindingDB Entry DOI: 10.7270/Q2930V4K
					More data for this Ligand-Target Pair