BDBM50378940 CHEMBL2011256::US9394290, 26

SMILES: C(c1ccc(nc1)-c1cccnc1)n1ccnc1

InChI Key: InChIKey=AILVDOWAXGVJGR-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50378940   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM50378940 (CHEMBL2011256 | US9394290, 26) Show SMILES C(c1ccc(nc1)-c1cccnc1)n1ccnc1 Show InChI InChI=1S/C14H12N4/c1-2-13(9-15-5-1)14-4-3-12(8-17-14)10-18-7-6-16-11-18/h1-9,11H,10H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	502	n/a	n/a	n/a	n/a	n/a	37
UNIVERSITAET DES SAARLANDES CAMPUS SAARBRUECKEN US Patent					Assay Description V79MZ cells expressing human CYP11B1 and human CYP11B2 genes, respectively, were grown on 24-well cell culture plates (8×10^5 cells per well) w...				US Patent US9394290 (2016) BindingDB Entry DOI: 10.7270/Q24T6H86
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM50378940 (CHEMBL2011256 | US9394290, 26) Show SMILES C(c1ccc(nc1)-c1cccnc1)n1ccnc1 Show InChI InChI=1S/C14H12N4/c1-2-13(9-15-5-1)14-4-3-12(8-17-14)10-18-7-6-16-11-18/h1-9,11H,10H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	502	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detector				ACS Med Chem Lett 2: 559-564 (2011) Article DOI: 10.1021/ml100283h BindingDB Entry DOI: 10.7270/Q21R6RJ2
					More data for this Ligand-Target Pair
Cytochrome P450 11B2 (CYP11B2) (Homo sapiens (Human))	BDBM50378940 (CHEMBL2011256 | US9394290, 26) Show SMILES C(c1ccc(nc1)-c1cccnc1)n1ccnc1 Show InChI InChI=1S/C14H12N4/c1-2-13(9-15-5-1)14-4-3-12(8-17-14)10-18-7-6-16-11-18/h1-9,11H,10H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.96E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detector				ACS Med Chem Lett 2: 559-564 (2011) Article DOI: 10.1021/ml100283h BindingDB Entry DOI: 10.7270/Q21R6RJ2
					More data for this Ligand-Target Pair
Cytochrome P450 11B2 (CYP11B2) (Homo sapiens (Human))	BDBM50378940 (CHEMBL2011256 | US9394290, 26) Show SMILES C(c1ccc(nc1)-c1cccnc1)n1ccnc1 Show InChI InChI=1S/C14H12N4/c1-2-13(9-15-5-1)14-4-3-12(8-17-14)10-18-7-6-16-11-18/h1-9,11H,10H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.96E+3	n/a	n/a	n/a	n/a	n/a	37
UNIVERSITAET DES SAARLANDES CAMPUS SAARBRUECKEN US Patent					Assay Description V79MZ cells expressing human CYP11B1 and human CYP11B2 genes, respectively, were grown on 24-well cell culture plates (8×10^5 cells per well) w...				US Patent US9394290 (2016) BindingDB Entry DOI: 10.7270/Q24T6H86
					More data for this Ligand-Target Pair