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BDBM50379785 CHEMBL2011528

SMILES: N[C@H]1CN(C[C@@H]1c1cc(F)ccc1F)c1ccc(cn1)-n1ccc(OCc2ccccc2)cc1=O

InChI Key: InChIKey=QJQHBMMHTBWFLJ-NOZRDPDXSA-N

Data: 5 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50379785
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50379785 (CHEMBL2011528) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
Prosidion Ltd Curated by ChEMBL					Assay Description Inhibition of DPP8				Bioorg Med Chem Lett 22: 2464-9 (2012) Article DOI: 10.1016/j.bmcl.2012.02.010 BindingDB Entry DOI: 10.7270/Q2SX6F7V
Prosidion Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50379785 (CHEMBL2011528) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Prosidion Ltd Curated by ChEMBL					Assay Description Antagonist activity at human MCH1R expressed in CHO cells assessed as inhibition of MCH-induced response				Bioorg Med Chem Lett 22: 2464-9 (2012) Article DOI: 10.1016/j.bmcl.2012.02.010 BindingDB Entry DOI: 10.7270/Q2SX6F7V
Prosidion Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379785 (CHEMBL2011528) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Prosidion Ltd Curated by ChEMBL					Assay Description Inhibition of human ERG				Bioorg Med Chem Lett 22: 2464-9 (2012) Article DOI: 10.1016/j.bmcl.2012.02.010 BindingDB Entry DOI: 10.7270/Q2SX6F7V
Prosidion Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM50379785 (CHEMBL2011528) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
Prosidion Ltd Curated by ChEMBL					Assay Description Inhibition of DPP9				Bioorg Med Chem Lett 22: 2464-9 (2012) Article DOI: 10.1016/j.bmcl.2012.02.010 BindingDB Entry DOI: 10.7270/Q2SX6F7V
Prosidion Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50379785 (CHEMBL2011528) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.65E+3	n/a	n/a	n/a	n/a	n/a	n/a
Prosidion Ltd Curated by ChEMBL					Assay Description Inhibition of human recombinant DPP4 using H-Gly-Pro-7-amino-4-methylcoumarin as substrate assessed as inhibition of 7-amino-4-methylcoumarin formati...				Bioorg Med Chem Lett 22: 2464-9 (2012) Article DOI: 10.1016/j.bmcl.2012.02.010 BindingDB Entry DOI: 10.7270/Q2SX6F7V
Prosidion Ltd Curated by ChEMBL					More data for this Ligand-Target Pair