BDBM50380407 CHEMBL2018294

SMILES: CN1CCc2c(C1)c1cccc(C)c1n2Cc1ccc(cc1)C(=O)NO

InChI Key: InChIKey=OMTXCPOBTKYTBJ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50380407   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50380407 (CHEMBL2018294) Show SMILES CN1CCc2c(C1)c1cccc(C)c1n2Cc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C21H23N3O2/c1-14-4-3-5-17-18-13-23(2)11-10-19(18)24(20(14)17)12-15-6-8-16(9-7-15)21(25)22-26/h3-9,26H,10-13H2,1-2H3,(H,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.21E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM50380407 (CHEMBL2018294) Show SMILES CN1CCc2c(C1)c1cccc(C)c1n2Cc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C21H23N3O2/c1-14-4-3-5-17-18-13-23(2)11-10-19(18)24(20(14)17)12-15-6-8-16(9-7-15)21(25)22-26/h3-9,26H,10-13H2,1-2H3,(H,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34.7	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC6 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair