BDBM50380471 CHEMBL2018766

SMILES: CCN(CC)CCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1OC

InChI Key: InChIKey=QCGQLXYNIITCFY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50380471   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50380471 (CHEMBL2018766) Show SMILES CCN(CC)CCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1OC Show InChI InChI=1S/C21H24BrFN4O2/c1-4-27(5-2)8-9-29-20-12-18-15(11-19(20)28-3)21(25-13-24-18)26-17-7-6-14(22)10-16(17)23/h6-7,10-13H,4-5,8-9H2,1-3H3,(H,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Univ. Lille Nord de France Curated by ChEMBL					Assay Description Inhibition of recombinant human VEGFR-2 using poly(Glu4/Tyr) and [gamma32P]ATP as substrate after 1 hr by scintillation counting				J Med Chem 55: 1189-204 (2012) Article DOI: 10.1021/jm2013453 BindingDB Entry DOI: 10.7270/Q2086695
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50380471 (CHEMBL2018766) Show SMILES CCN(CC)CCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1OC Show InChI InChI=1S/C21H24BrFN4O2/c1-4-27(5-2)8-9-29-20-12-18-15(11-19(20)28-3)21(25-13-24-18)26-17-7-6-14(22)10-16(17)23/h6-7,10-13H,4-5,8-9H2,1-3H3,(H,24,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Univ. Lille Nord de France Curated by ChEMBL					Assay Description Inhibition of human EGFR expressed in human A431 cells using poly(Glu4/Tyr) and [gamma32P]ATP as substrate after 1 hr by scintillation counting				J Med Chem 55: 1189-204 (2012) Article DOI: 10.1021/jm2013453 BindingDB Entry DOI: 10.7270/Q2086695
					More data for this Ligand-Target Pair