BDBM50380683 CHEMBL2017507

SMILES: CCOP(=O)(OCC)C(Cc1ccccc1)c1sc2ccccc2c1C

InChI Key: InChIKey=VZXCBYCDPRUZAN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50380683   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential M8 protein (TRPM8) (Canis lupus familiaris (Dog))	BDBM50380683 (CHEMBL2017507) Show SMILES CCOP(=O)(OCC)C(Cc1ccccc1)c1sc2ccccc2c1C Show InChI InChI=1S/C21H25O3PS/c1-4-23-25(22,24-5-2)19(15-17-11-7-6-8-12-17)21-16(3)18-13-9-10-14-20(18)26-21/h6-14,19H,4-5,15H2,1-3H3	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
					More data for this Ligand-Target Pair