BDBM50380966 CHEMBL2016921

SMILES: COc1ccc2[nH]c(=O)c(cc2c1)-c1nc2CCN(Cc2[nH]1)C(=O)CN1CCCCC1

InChI Key: InChIKey=KSSLFXDVLGKDNC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50380966   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50380966 (CHEMBL2016921) Show SMILES COc1ccc2[nH]c(=O)c(cc2c1)-c1nc2CCN(Cc2[nH]1)C(=O)CN1CCCCC1 Show InChI InChI=1S/C23H27N5O3/c1-31-16-5-6-18-15(11-16)12-17(23(30)26-18)22-24-19-7-10-28(13-20(19)25-22)21(29)14-27-8-3-2-4-9-27/h5-6,11-12H,2-4,7-10,13-14H2,1H3,(H,24,25)(H,26,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant VEGFR-2 kinase domain by homogeneous time-resolved fluorescence assay				Bioorg Med Chem Lett 22: 2837-42 (2012) Article DOI: 10.1016/j.bmcl.2012.02.073 BindingDB Entry DOI: 10.7270/Q2RN38W3
					More data for this Ligand-Target Pair