BDBM50380997 BROUSSONIN B
SMILES: COc1cc(O)ccc1CCCc1ccc(O)cc1
InChI Key: InChIKey=CJJJQWAYMRTLJT-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Proteasome subunit beta type-5 (Rattus norvegicus) | BDBM50380997 (BROUSSONIN B) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Agricultural and Food Biotechnology Curated by ChEMBL | Assay Description Inhibition of chymotrypsin-like activity of rat liver 26 proteasome assessed as decrease in fluorescence using succinyl-Leu-Leu-Val-Tyr-4-methylcouma... | Eur J Med Chem 167: 291-311 (2019) Article DOI: 10.1016/j.ejmech.2019.01.044 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic lipase (Sus scrofa (Pig)) | BDBM50380997 (BROUSSONIN B) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.54E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chungbuk National University Curated by ChEMBL | Assay Description Inhibition of porcine pancreatic lipase using p-nitrophenylbutyrate as substrate preincubated for 15 mins prior substrate addition measured after 15 ... | Bioorg Med Chem Lett 22: 2760-3 (2012) Article DOI: 10.1016/j.bmcl.2012.02.088 BindingDB Entry DOI: 10.7270/Q2H41SFC | |||||||||||
More data for this Ligand-Target Pair |