BDBM50381039 CHEMBL2017347

SMILES: Fc1ccc(Nc2nc3c(cccc3c3sccc23)-c2nnc[nH]2)cc1

InChI Key: InChIKey=HSBXTJAEFSRBOW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50381039   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50381039 (CHEMBL2017347) Show SMILES Fc1ccc(Nc2nc3c(cccc3c3sccc23)-c2nnc[nH]2)cc1 Show InChI InChI=1S/C19H12FN5S/c20-11-4-6-12(7-5-11)23-19-15-8-9-26-17(15)13-2-1-3-14(16(13)24-19)18-21-10-22-25-18/h1-10H,(H,23,24)(H,21,22,25)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Cylene Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate and 30 uM ATP by radiometric assay				Bioorg Med Chem Lett 22: 3327-31 (2012) Article DOI: 10.1016/j.bmcl.2012.02.099 BindingDB Entry DOI: 10.7270/Q2057GZB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50381039 (CHEMBL2017347) Show SMILES Fc1ccc(Nc2nc3c(cccc3c3sccc23)-c2nnc[nH]2)cc1 Show InChI InChI=1S/C19H12FN5S/c20-11-4-6-12(7-5-11)23-19-15-8-9-26-17(15)13-2-1-3-14(16(13)24-19)18-21-10-22-25-18/h1-10H,(H,23,24)(H,21,22,25)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Cylene Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate and 5 uM ATP by radiometric assay				Bioorg Med Chem Lett 22: 3327-31 (2012) Article DOI: 10.1016/j.bmcl.2012.02.099 BindingDB Entry DOI: 10.7270/Q2057GZB
					More data for this Ligand-Target Pair