BDBM50381253 CHEMBL2018670
SMILES: Cc1noc2c(Cc3ccc(cc3)[N+]([O-])=O)nn(Cc3n[nH]c(=S)n3C)c(=O)c12
InChI Key: InChIKey=LRWHVVRSHKMVRN-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM50381253 (CHEMBL2018670) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Hacettepe Curated by ChEMBL | Assay Description Inhibition of human recombinant COX2 by fluorescence assay | Bioorg Med Chem 20: 2912-22 (2012) Article DOI: 10.1016/j.bmc.2012.03.021 BindingDB Entry DOI: 10.7270/Q2F76DKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM50381253 (CHEMBL2018670) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.77E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Hacettepe Curated by ChEMBL | Assay Description Inhibition of ovine COX1 by fluorescence assay | Bioorg Med Chem 20: 2912-22 (2012) Article DOI: 10.1016/j.bmc.2012.03.021 BindingDB Entry DOI: 10.7270/Q2F76DKX | |||||||||||
More data for this Ligand-Target Pair |