BDBM50381306 CHEMBL2019120

SMILES: CNC(=O)[C@H]1C[C@@H]1c1ccc(c(OC)c1)-c1nc2snc(C3CCCCC3)c2c(=O)[nH]1

InChI Key: InChIKey=CKPCTIDEXRIQJB-CVEARBPZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50381306   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 7 (Homo sapiens (Human))	BDBM50381306 (CHEMBL2019120) Show SMILES CNC(=O)[C@H]1C[C@@H]1c1ccc(c(OC)c1)-c1nc2snc(C3CCCCC3)c2c(=O)[nH]1 |r| Show InChI InChI=1S/C23H26N4O3S/c1-24-21(28)16-11-15(16)13-8-9-14(17(10-13)30-2)20-25-22(29)18-19(27-31-23(18)26-20)12-6-4-3-5-7-12/h8-10,12,15-16H,3-7,11H2,1-2H3,(H,24,28)(H,25,26,29)/t15-,16+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Glenmark Pharmaceuticals Limited Curated by ChEMBL					Assay Description Displacement of [3H]-cAMP from human recombinant PDE7A				Bioorg Med Chem Lett 22: 3223-8 (2012) Article DOI: 10.1016/j.bmcl.2012.03.025 BindingDB Entry DOI: 10.7270/Q2NP25F2
					More data for this Ligand-Target Pair