BDBM50381412 CHEMBL2017186

SMILES: CC[C@@H]1C[C@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(C)=O)c2nc(ccc2N1C(=O)OC(C)C)N(C)C

InChI Key: InChIKey=NUXKXDXUQRXXFZ-IRLDBZIGSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50381412   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50381412 (CHEMBL2017186) Show SMILES CC[C@@H]1C[C@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(C)=O)c2nc(ccc2N1C(=O)OC(C)C)N(C)C |r| Show InChI InChI=1S/C27H32F6N4O3/c1-7-20-13-22(24-21(8-9-23(34-24)35(5)6)37(20)25(39)40-15(2)3)36(16(4)38)14-17-10-18(26(28,29)30)12-19(11-17)27(31,32)33/h8-12,15,20,22H,7,13-14H2,1-6H3/t20-,22+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	948	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Inhibition of CETP in human plasma assessed as reduction in fluorescent intensity by fluorescence analysis				Bioorg Med Chem Lett 22: 3056-62 (2012) Article DOI: 10.1016/j.bmcl.2012.03.075 BindingDB Entry DOI: 10.7270/Q28G8MQT
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