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SMILES: CC[C@@H]1C[C@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2nnn(C)n2)c2nc(ccc2N1C(=O)OC(C)C)N1CCOCC1

InChI Key: InChIKey=WFJPNLZYPUFRCJ-GGAORHGYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50381433   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cholesteryl ester transfer protein


(Homo sapiens (Human))		BDBM50381433
PNG
(CHEMBL2017382)
Show SMILES CC[C@@H]1C[C@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2nnn(C)n2)c2nc(ccc2N1C(=O)OC(C)C)N1CCOCC1 |r|
Show InChI InChI=1S/C29H34F6N8O3/c1-5-21-15-23(25-22(43(21)27(44)46-17(2)3)6-7-24(36-25)41-8-10-45-11-9-41)42(26-37-39-40(4)38-26)16-18-12-19(28(30,31)32)14-20(13-18)29(33,34)35/h6-7,12-14,17,21,23H,5,8-11,15-16H2,1-4H3/t21-,23+/m1/s1
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Article
PubMed
n/an/a 2.50E+4n/an/an/an/an/an/a



Centro de Investigaci�n Lilly

Curated by ChEMBL


Assay Description
Inhibition of CETP in human plasma assessed as reduction in fluorescent intensity by fluorescence analysis

Bioorg Med Chem Lett 22: 3056-62 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.075
BindingDB Entry DOI: 10.7270/Q28G8MQT
More data for this
Ligand-Target Pair