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SMILES: CCC1CC(N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(C)=O)c2sccc2N1C(=O)OC(C)C

InChI Key: InChIKey=FWFBXCGTTOEINR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50381439   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cholesteryl ester transfer protein


(Homo sapiens (Human))		BDBM50381439
PNG
(CHEMBL2017180)
Show SMILES CCC1CC(N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(C)=O)c2sccc2N1C(=O)OC(C)C
Show InChI InChI=1S/C24H26F6N2O3S/c1-5-18-11-20(21-19(6-7-36-21)32(18)22(34)35-13(2)3)31(14(4)33)12-15-8-16(23(25,26)27)10-17(9-15)24(28,29)30/h6-10,13,18,20H,5,11-12H2,1-4H3
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MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.60E+4n/an/an/an/an/an/a



Centro de Investigaci�n Lilly

Curated by ChEMBL


Assay Description
Inhibition of CETP in human plasma assessed as reduction in fluorescent intensity by fluorescence analysis

Bioorg Med Chem Lett 22: 3056-62 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.075
BindingDB Entry DOI: 10.7270/Q28G8MQT
More data for this
Ligand-Target Pair