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SMILES: [#6]\[#6](-[#6])=[#6]\[#6]-[#8]-c1cc(-[#8]-c2ccc(cc2)S(=O)(=O)[#6]-2-[#6]-[#6]-2)cc(c1)-[#6](=O)-[#7]-c1nccn2ccnc12

InChI Key: InChIKey=JZAUIMMPSNHUHI-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50381627   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hexokinase-4


(Homo sapiens (Human))		BDBM50381627
PNG
(CHEMBL2023062)
Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#8]-c1cc(-[#8]-c2ccc(cc2)S(=O)(=O)[#6]-2-[#6]-[#6]-2)cc(c1)-[#6](=O)-[#7]-c1nccn2ccnc12
Show InChI InChI=1S/C27H26N4O5S/c1-18(2)9-14-35-21-15-19(27(32)30-25-26-29-11-13-31(26)12-10-28-25)16-22(17-21)36-20-3-5-23(6-4-20)37(33,34)24-7-8-24/h3-6,9-13,15-17,24H,7-8,14H2,1-2H3,(H,28,30,32)
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Similars
Article
PubMed
n/an/an/an/a>1.00E+3n/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Activation of human recombinant glucokinase expressed in Escherichia coli BL21(DE3) coexpressing G6PDH assessed as glucose 6-phosphate formation by s...

Bioorg Med Chem 20: 2982-91 (2012)


Article DOI: 10.1016/j.bmc.2012.03.008
BindingDB Entry DOI: 10.7270/Q2H1331F
More data for this
Ligand-Target Pair