Found 4 hits for monomerid = 50381950 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Platelet-derived growth factor receptor beta
(Homo sapiens (Human)) | BDBM50381950
(CHEMBL2023494)Show SMILES COc1ccc2c(Oc3ccc(CC(=O)Nc4cc(C)cc(CN(C)C)c4)c(OC)c3)ccnc2c1 Show InChI InChI=1S/C29H31N3O4/c1-19-12-20(18-32(2)3)14-22(13-19)31-29(33)15-21-6-7-24(17-28(21)35-5)36-27-10-11-30-26-16-23(34-4)8-9-25(26)27/h6-14,16-17H,15,18H2,1-5H3,(H,31,33) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of PDGFRbeta |
Bioorg Med Chem Lett 22: 3050-5 (2012)
Article DOI: 10.1016/j.bmcl.2012.03.074
BindingDB Entry DOI: 10.7270/Q298881Z |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 [K633Q]
(Homo sapiens (Human)) | BDBM50381950
(CHEMBL2023494)Show SMILES COc1ccc2c(Oc3ccc(CC(=O)Nc4cc(C)cc(CN(C)C)c4)c(OC)c3)ccnc2c1 Show InChI InChI=1S/C29H31N3O4/c1-19-12-20(18-32(2)3)14-22(13-19)31-29(33)15-21-6-7-24(17-28(21)35-5)36-27-10-11-30-26-16-23(34-4)8-9-25(26)27/h6-14,16-17H,15,18H2,1-5H3,(H,31,33) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of Flt3 |
Bioorg Med Chem Lett 22: 3050-5 (2012)
Article DOI: 10.1016/j.bmcl.2012.03.074
BindingDB Entry DOI: 10.7270/Q298881Z |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50381950
(CHEMBL2023494)Show SMILES COc1ccc2c(Oc3ccc(CC(=O)Nc4cc(C)cc(CN(C)C)c4)c(OC)c3)ccnc2c1 Show InChI InChI=1S/C29H31N3O4/c1-19-12-20(18-32(2)3)14-22(13-19)31-29(33)15-21-6-7-24(17-28(21)35-5)36-27-10-11-30-26-16-23(34-4)8-9-25(26)27/h6-14,16-17H,15,18H2,1-5H3,(H,31,33) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of KDR |
Bioorg Med Chem Lett 22: 3050-5 (2012)
Article DOI: 10.1016/j.bmcl.2012.03.074
BindingDB Entry DOI: 10.7270/Q298881Z |
More data for this
Ligand-Target Pair | |
Macrophage colony-stimulating factor 1 receptor
(Homo sapiens (Human)) | BDBM50381950
(CHEMBL2023494)Show SMILES COc1ccc2c(Oc3ccc(CC(=O)Nc4cc(C)cc(CN(C)C)c4)c(OC)c3)ccnc2c1 Show InChI InChI=1S/C29H31N3O4/c1-19-12-20(18-32(2)3)14-22(13-19)31-29(33)15-21-6-7-24(17-28(21)35-5)36-27-10-11-30-26-16-23(34-4)8-9-25(26)27/h6-14,16-17H,15,18H2,1-5H3,(H,31,33) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of CSF-1R |
Bioorg Med Chem Lett 22: 3050-5 (2012)
Article DOI: 10.1016/j.bmcl.2012.03.074
BindingDB Entry DOI: 10.7270/Q298881Z |
More data for this
Ligand-Target Pair | |
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