BDBM50381983 CHEMBL2023929

SMILES: Fc1ccccc1C(=O)Nc1ccc(-c2nnc(NCCCN3CCCCC3)o2)c(c1)C(F)(F)F

InChI Key: InChIKey=KVDQWUVURWICGP-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50381983   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50381983 (CHEMBL2023929) Show SMILES Fc1ccccc1C(=O)Nc1ccc(-c2nnc(NCCCN3CCCCC3)o2)c(c1)C(F)(F)F Show InChI InChI=1S/C24H25F4N5O2/c25-20-8-3-2-7-18(20)21(34)30-16-9-10-17(19(15-16)24(26,27)28)22-31-32-23(35-22)29-11-6-14-33-12-4-1-5-13-33/h2-3,7-10,15H,1,4-6,11-14H2,(H,29,32)(H,30,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]Dofetilide from human ERG expressed in CHO-K1 cells by scintillation proximity assay				Bioorg Med Chem Lett 22: 3560-3 (2012) Article DOI: 10.1016/j.bmcl.2012.03.040 BindingDB Entry DOI: 10.7270/Q21V5FZC
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor protein alpha-7 subunit (Homo sapiens (Human))	BDBM50381983 (CHEMBL2023929) Show SMILES Fc1ccccc1C(=O)Nc1ccc(-c2nnc(NCCCN3CCCCC3)o2)c(c1)C(F)(F)F Show InChI InChI=1S/C24H25F4N5O2/c25-20-8-3-2-7-18(20)21(34)30-16-9-10-17(19(15-16)24(26,27)28)22-31-32-23(35-22)29-11-6-14-33-12-4-1-5-13-33/h2-3,7-10,15H,1,4-6,11-14H2,(H,29,32)(H,30,34)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Agonist activity at human alpha7 nAChR expressed in GH4C1 cells by FLIPR assay				Bioorg Med Chem Lett 22: 3560-3 (2012) Article DOI: 10.1016/j.bmcl.2012.03.040 BindingDB Entry DOI: 10.7270/Q21V5FZC
					More data for this Ligand-Target Pair