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SMILES: COc1ccc(Cn2c(C)nc(Cc3ccc(N)cc3)c2Cc2ccc(Cl)cc2)cc1

InChI Key: InChIKey=MHEKRKYUGZKZOH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50382114   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein Mdm4


(Homo sapiens (Human))		BDBM50382114
PNG
(CHEMBL2024320)
Show SMILES COc1ccc(Cn2c(C)nc(Cc3ccc(N)cc3)c2Cc2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C26H26ClN3O/c1-18-29-25(15-19-5-11-23(28)12-6-19)26(16-20-3-9-22(27)10-4-20)30(18)17-21-7-13-24(31-2)14-8-21/h3-14H,15-17,28H2,1-2H3
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 7.00E+4n/an/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Inhibition of p53 derived peptide binding to MDM4 using fluorescent dye Cy5 by TR-FRET assay

Bioorg Med Chem Lett 22: 3498-502 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.083
BindingDB Entry DOI: 10.7270/Q2D21ZM2
More data for this
Ligand-Target Pair