BindingDB logo
myBDB logout

null

SMILES: OCCc1cccc(NC(=O)Nc2ccc(Cl)c(c2)C(F)(F)F)c1

InChI Key: InChIKey=BKCXLZYKRXUEKU-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50382239   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM50382239
PNG
(CHEMBL2024666)
Show SMILES OCCc1cccc(NC(=O)Nc2ccc(Cl)c(c2)C(F)(F)F)c1
Show InChI InChI=1S/C16H14ClF3N2O2/c17-14-5-4-12(9-13(14)16(18,19)20)22-15(24)21-11-3-1-2-10(8-11)6-7-23/h1-5,8-9,23H,6-7H2,(H2,21,22,24)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 230n/an/an/an/an/an/a



Bayer Yakuhin, Ltd

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPV1 expressed in CHOluc9aeq cells assessed as inhibition of capsaicin-stimulated response by aequorin and CRE-lucifear...

Bioorg Med Chem Lett 22: 3408-11 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.108
BindingDB Entry DOI: 10.7270/Q2C24XF7
More data for this
Ligand-Target Pair