BDBM50382323 CHEMBL2024690
SMILES: Cc1cccc(n1)-n1nccc1-c1ccc2nc[nH]c(=O)c2c1
InChI Key: InChIKey=QJNPMPKTEIRZQN-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ALK5 (Mus musculus) | BDBM50382323 (CHEMBL2024690) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 73 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of ALK5 in mouse NIH/3T3 cells by smad binding element reporter based assay | Bioorg Med Chem Lett 22: 3392-7 (2012) Article DOI: 10.1016/j.bmcl.2012.04.013 BindingDB Entry DOI: 10.7270/Q2QC04H9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 (Homo sapiens (Human)) | BDBM50382323 (CHEMBL2024690) | PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of ALK5 | Bioorg Med Chem Lett 22: 3392-7 (2012) Article DOI: 10.1016/j.bmcl.2012.04.013 BindingDB Entry DOI: 10.7270/Q2QC04H9 | |||||||||||
More data for this Ligand-Target Pair |