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BDBM50382450 CHEMBL2023356

SMILES: COc1ccc(cc1[C@H]1C[C@@H]1CN)-c1ccccc1C

InChI Key: InChIKey=WXEBMCPVABEGHW-ZBFHGGJFSA-N

Data: 1 EC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50382450   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))
BDBM50382450
PNG
(CHEMBL2023356)
Show SMILES COc1ccc(cc1[C@H]1C[C@@H]1CN)-c1ccccc1C |r|
Show InChI InChI=1S/C18H21NO/c1-12-5-3-4-6-15(12)13-7-8-18(20-2)17(9-13)16-10-14(16)11-19/h3-9,14,16H,10-11,19H2,1-2H3/t14-,16+/m1/s1
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PC cid
PC sid
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Similars

Article
PubMed
n/an/an/an/a 3.47E+3n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Agonist activity at human 5HT2C receptor expressed in HEK293 cells assessed as calcium flux measured every sec for 3 mins by FLIPR assay


ACS Med Chem Lett 2: 929-932 (2011)


Article DOI: 10.1021/ml200206z
BindingDB Entry DOI: 10.7270/Q2959JKS
More data for this
Ligand-Target Pair