null

SMILES: NCCSC(c1ccccc1)(c1ccccc1)c1cccc(c1)C(N)=O

InChI Key: InChIKey=ZEAMYFNKGIBVEF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50382570   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50382570 (CHEMBL2024125) Show SMILES NCCSC(c1ccccc1)(c1ccccc1)c1cccc(c1)C(N)=O Show InChI InChI=1S/C22H22N2OS/c23-14-15-26-22(18-9-3-1-4-10-18,19-11-5-2-6-12-19)20-13-7-8-17(16-20)21(24)25/h1-13,16H,14-15,23H2,(H2,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Beatson Institute for Cancer Research Curated by ChEMBL					Assay Description Inhibition of N-terminal hexa-histidine tagged human cloned Eg5 (1 to 368 amino acids) expressed in Escherichia coli BL21 (DE3) assessed as reduction...				J Med Chem 55: 1511-25 (2012) Article DOI: 10.1021/jm201195m BindingDB Entry DOI: 10.7270/Q2CZ386T
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50382570 (CHEMBL2024125) Show SMILES NCCSC(c1ccccc1)(c1ccccc1)c1cccc(c1)C(N)=O Show InChI InChI=1S/C22H22N2OS/c23-14-15-26-22(18-9-3-1-4-10-18,19-11-5-2-6-12-19)20-13-7-8-17(16-20)21(24)25/h1-13,16H,14-15,23H2,(H2,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Beatson Institute for Cancer Research Curated by ChEMBL					Assay Description Inhibition of human N-terminal His6-tagged Eg5 (1 to 368 amino acid residues) motor domain basal ATPase activity expressed in Escherichia coli BL21 (...				J Med Chem 56: 1878-93 (2013) Article DOI: 10.1021/jm3014597 BindingDB Entry DOI: 10.7270/Q20866NN
					More data for this Ligand-Target Pair