BDBM50382828 CHEMBL2023424

SMILES: Clc1ccc2NC(=O)N(Cc3ccc(cc3)C(=O)N(C3CC3)C3CCCCCC3)S(=O)(=O)c2c1

InChI Key: InChIKey=JFDYBPLEQYOOOP-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50382828   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50382828 (CHEMBL2023424) Show SMILES Clc1ccc2NC(=O)N(Cc3ccc(cc3)C(=O)N(C3CC3)C3CCCCCC3)S(=O)(=O)c2c1 Show InChI InChI=1S/C25H28ClN3O4S/c26-19-11-14-22-23(15-19)34(32,33)28(25(31)27-22)16-17-7-9-18(10-8-17)24(30)29(21-12-13-21)20-5-3-1-2-4-6-20/h7-11,14-15,20-21H,1-6,12-13,16H2,(H,27,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	84	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPA				Bioorg Med Chem Lett 22: 2748-52 (2012) Article DOI: 10.1016/j.bmcl.2012.02.095 BindingDB Entry DOI: 10.7270/Q22F7PGX
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50382828 (CHEMBL2023424) Show SMILES Clc1ccc2NC(=O)N(Cc3ccc(cc3)C(=O)N(C3CC3)C3CCCCCC3)S(=O)(=O)c2c1 Show InChI InChI=1S/C25H28ClN3O4S/c26-19-11-14-22-23(15-19)34(32,33)28(25(31)27-22)16-17-7-9-18(10-8-17)24(30)29(21-12-13-21)20-5-3-1-2-4-6-20/h7-11,14-15,20-21H,1-6,12-13,16H2,(H,27,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPA				Bioorg Med Chem Lett 22: 2748-52 (2012) Article DOI: 10.1016/j.bmcl.2012.02.095 BindingDB Entry DOI: 10.7270/Q22F7PGX
					More data for this Ligand-Target Pair