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SMILES: COc1ccc(cc1)-n1c(O)c(CC(=O)Nc2ccccc2)n(CCc2cccs2)c1=S

InChI Key: InChIKey=HLHFLJWIOFKTOP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50383082   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kinesin-like protein KIF11


(Homo sapiens (Human))		BDBM50383082
PNG
(CHEMBL2031569)
Show SMILES COc1ccc(cc1)-n1c(O)c(CC(=O)Nc2ccccc2)n(CCc2cccs2)c1=S
Show InChI InChI=1S/C24H23N3O3S2/c1-30-19-11-9-18(10-12-19)27-23(29)21(16-22(28)25-17-6-3-2-4-7-17)26(24(27)31)14-13-20-8-5-15-32-20/h2-12,15,29H,13-14,16H2,1H3,(H,25,28)
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Similars
Article
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



Korea Institute of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of Eg5 ATPase activity by pyruvate kinase/lactate dehydrogenase-linked assay

J Med Chem 55: 2561-73 (2012)


Article DOI: 10.1021/jm201290v
BindingDB Entry DOI: 10.7270/Q2M909P0
More data for this
Ligand-Target Pair