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SMILES: COc1ccc(NC(=O)Cc2c(O)n(-c3ccccc3)c(=S)n2CCc2sccc2C)cc1

InChI Key: InChIKey=SFNLPTUZEIWHCT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50383086   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kinesin-like protein KIF11


(Homo sapiens (Human))		BDBM50383086
PNG
(CHEMBL2031571)
Show SMILES COc1ccc(NC(=O)Cc2c(O)n(-c3ccccc3)c(=S)n2CCc2sccc2C)cc1
Show InChI InChI=1S/C25H25N3O3S2/c1-17-13-15-33-22(17)12-14-27-21(16-23(29)26-18-8-10-20(31-2)11-9-18)24(30)28(25(27)32)19-6-4-3-5-7-19/h3-11,13,15,30H,12,14,16H2,1-2H3,(H,26,29)
PDB
MMDB

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Similars
Article
PubMed
n/an/a 2.40E+3n/an/an/an/an/an/a



Korea Institute of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of Eg5 ATPase activity by pyruvate kinase/lactate dehydrogenase-linked assay

J Med Chem 55: 2561-73 (2012)


Article DOI: 10.1021/jm201290v
BindingDB Entry DOI: 10.7270/Q2M909P0
More data for this
Ligand-Target Pair