BDBM50383229 CHEMBL2032175

SMILES: Clc1ccc(cc1)C1N(CCc2sccc12)C(=O)Nc1ccccc1

InChI Key: InChIKey=VKNPNFFVRYOJAD-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50383229   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50383229 (CHEMBL2032175) Show SMILES Clc1ccc(cc1)C1N(CCc2sccc12)C(=O)Nc1ccccc1 Show InChI InChI=1S/C20H17ClN2OS/c21-15-8-6-14(7-9-15)19-17-11-13-25-18(17)10-12-23(19)20(24)22-16-4-2-1-3-5-16/h1-9,11,13,19H,10,12H2,(H,22,24)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382
					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (TRPM8) (Rattus norvegicus (Rat))	BDBM50383229 (CHEMBL2032175) Show SMILES Clc1ccc(cc1)C1N(CCc2sccc12)C(=O)Nc1ccccc1 Show InChI InChI=1S/C20H17ClN2OS/c21-15-8-6-14(7-9-15)19-17-11-13-25-18(17)10-12-23(19)20(24)22-16-4-2-1-3-5-16/h1-9,11,13,19H,10,12H2,(H,22,24)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat TRPM8 expressed in CHO cells assessed as inhibition of icilin-induced Ca2+ influx incubated 2.5 mins prior icilin inductio...				J Med Chem 55: 1593-611 (2012) Article DOI: 10.1021/jm2013634 BindingDB Entry DOI: 10.7270/Q2TT4S0C
					More data for this Ligand-Target Pair