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BDBM50383372 CHEMBL1998001

SMILES: CN(C)c1ccc(\C=C(/C#N)c2ccccc2)cc1

InChI Key: InChIKey=HYAJIHDALOHMPT-FOWTUZBSSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50383372   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Peroxisome proliferator-activated receptor delta


(Mus musculus)
BDBM50383372
PNG
(CHEMBL1998001)
Show SMILES CN(C)c1ccc(\C=C(/C#N)c2ccccc2)cc1
Show InChI InChI=1S/C17H16N2/c1-19(2)17-10-8-14(9-11-17)12-16(13-18)15-6-4-3-5-7-15/h3-12H,1-2H3/b16-12+
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a>500n/an/an/an/an/an/a



Philipps University

Curated by ChEMBL


Assay Description
Inverse agonist activity at PPARbeta/delta in mouse C2C12 cells assessed as inhibition of Angptl4 expression after 24 hrs by RT-qPCR analysis


J Med Chem 55: 2858-68 (2012)


Article DOI: 10.1021/jm2017122
BindingDB Entry DOI: 10.7270/Q2XK8GK9
More data for this
Ligand-Target Pair