BDBM50383438 CHEMBL2031592

SMILES: Cc1cc(C2CCN(CC2)C(=O)[C@H]2C[C@](C)(N)C[C@@H]2c2ccc(F)cc2F)n(n1)-c1ccc(F)c(Cl)c1

InChI Key: InChIKey=GMOFRPHSPZPTTF-RZIGYZOXSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50383438   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prolylcarboxypeptidase (PRCP) (Homo sapiens (Human))	BDBM50383438 (CHEMBL2031592) Show SMILES Cc1cc(C2CCN(CC2)C(=O)[C@H]2C[C@](C)(N)C[C@@H]2c2ccc(F)cc2F)n(n1)-c1ccc(F)c(Cl)c1 |r| Show InChI InChI=1S/C28H30ClF3N4O/c1-16-11-26(36(34-16)19-4-6-24(31)23(29)13-19)17-7-9-35(10-8-17)27(37)22-15-28(2,33)14-21(22)20-5-3-18(30)12-25(20)32/h3-6,11-13,17,21-22H,7-10,14-15,33H2,1-2H3/t21-,22+,28-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	635	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human PrCP				Bioorg Med Chem Lett 22: 2818-22 (2012) Article DOI: 10.1016/j.bmcl.2012.02.077 BindingDB Entry DOI: 10.7270/Q2J967D7
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