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SMILES: O=C(N1CCC1)c1cccc(n1)-c1nnc(s1)N1CCC(CC1)N1CCCCC1

InChI Key: InChIKey=IJTFIYCVMQYFLZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50383448   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))		BDBM50383448
PNG
(CHEMBL2031608)
Show SMILES O=C(N1CCC1)c1cccc(n1)-c1nnc(s1)N1CCC(CC1)N1CCCCC1
Show InChI InChI=1S/C21H28N6OS/c28-20(26-12-5-13-26)18-7-4-6-17(22-18)19-23-24-21(29-19)27-14-8-16(9-15-27)25-10-2-1-3-11-25/h4,6-7,16H,1-3,5,8-15H2
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PC cid
PC sid
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Article
PubMed
 4.40n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK cell membranes after 30 mins by scintillati...

Bioorg Med Chem Lett 22: 3354-7 (2012)


Article DOI: 10.1016/j.bmcl.2012.02.076
BindingDB Entry DOI: 10.7270/Q2DN462S
More data for this
Ligand-Target Pair