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SMILES: O=c1ccc2c(cccc2[nH]1)-c1nnc(s1)N1CCC(CC1)N1CCCCC1

InChI Key: InChIKey=MAXOGUXZCWXAII-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50383455   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))		BDBM50383455
PNG
(CHEMBL2031615)
Show SMILES O=c1ccc2c(cccc2[nH]1)-c1nnc(s1)N1CCC(CC1)N1CCCCC1
Show InChI InChI=1S/C21H25N5OS/c27-19-8-7-16-17(5-4-6-18(16)22-19)20-23-24-21(28-20)26-13-9-15(10-14-26)25-11-2-1-3-12-25/h4-8,15H,1-3,9-14H2,(H,22,27)
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Article
PubMed
 20n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK cell membranes after 30 mins by scintillati...

Bioorg Med Chem Lett 22: 3354-7 (2012)


Article DOI: 10.1016/j.bmcl.2012.02.076
BindingDB Entry DOI: 10.7270/Q2DN462S
More data for this
Ligand-Target Pair