null
SMILES: COC(OC)C1=C(C(C(C=N1)C(O)=O)c1cccc(Cl)c1)C(=O)OC\C=C\c1ccccc1
InChI Key: InChIKey=GMLOJRQUIGOZQC-JXMROGBWSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human)) | BDBM50383773 (CHEMBL2030591) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ajinomoto Pharmaceuticals Co. Ltd Curated by ChEMBL | Assay Description Inhibition of N-type voltage-dependent calcium channel CaV2.2 in human IMR32 cells assessed as inhibition of KCl-induced increase in intracellular ca... | Bioorg Med Chem Lett 22: 3639-42 (2012) Article DOI: 10.1016/j.bmcl.2012.04.051 BindingDB Entry DOI: 10.7270/Q2QV3NJX | |||||||||||
More data for this Ligand-Target Pair |