BindingDB logo
myBDB logout

null

SMILES: COC(OC)C1=C(C(C(C=N1)C(O)=O)c1ccc(Cl)c(Cl)c1)C(=O)OC\C=C\c1ccccc1

InChI Key: InChIKey=WGXWXSSRJJNYKH-RMKNXTFCSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50383776   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Voltage-dependent N-type calcium channel subunit alpha-1B


(Homo sapiens (Human))		BDBM50383776
PNG
(CHEMBL2030594)
Show SMILES COC(OC)C1=C(C(C(C=N1)C(O)=O)c1ccc(Cl)c(Cl)c1)C(=O)OC\C=C\c1ccccc1 |c:9,t:5|
Show InChI InChI=1S/C25H23Cl2NO6/c1-32-25(33-2)22-21(24(31)34-12-6-9-15-7-4-3-5-8-15)20(17(14-28-22)23(29)30)16-10-11-18(26)19(27)13-16/h3-11,13-14,17,20,25H,12H2,1-2H3,(H,29,30)/b9-6+
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 520n/an/an/an/an/an/a



Ajinomoto Pharmaceuticals Co. Ltd

Curated by ChEMBL


Assay Description
Inhibition of N-type voltage-dependent calcium channel CaV2.2 in human IMR32 cells assessed as inhibition of KCl-induced increase in intracellular ca...

Bioorg Med Chem Lett 22: 3639-42 (2012)


Article DOI: 10.1016/j.bmcl.2012.04.051
BindingDB Entry DOI: 10.7270/Q2QV3NJX
More data for this
Ligand-Target Pair