BDBM50384011 CHEMBL2032293

SMILES: Nc1ncc(cc1-c1nc2ccc(F)cc2o1)-c1cnn(c1)C1CCN(CCO)CC1

InChI Key: InChIKey=KUINAMJHQUTSAV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50384011   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50384011 (CHEMBL2032293) Show SMILES Nc1ncc(cc1-c1nc2ccc(F)cc2o1)-c1cnn(c1)C1CCN(CCO)CC1 Show InChI InChI=1S/C22H23FN6O2/c23-16-1-2-19-20(10-16)31-22(27-19)18-9-14(11-25-21(18)24)15-12-26-29(13-15)17-3-5-28(6-4-17)7-8-30/h1-2,9-13,17,30H,3-8H2,(H2,24,25)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis				Bioorg Med Chem Lett 22: 4044-8 (2012) Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4
					More data for this Ligand-Target Pair