BDBM50384031 CHEMBL2032162

SMILES: Nc1ncc(cc1-c1nc2ccc(Oc3ccncn3)cc2o1)-c1cnn(c1)C1CCNCC1

InChI Key: InChIKey=XXOIYMNKKVTMMW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50384031   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50384031 (CHEMBL2032162) Show SMILES Nc1ncc(cc1-c1nc2ccc(Oc3ccncn3)cc2o1)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C24H22N8O2/c25-23-19(9-15(11-28-23)16-12-30-32(13-16)17-3-6-26-7-4-17)24-31-20-2-1-18(10-21(20)34-24)33-22-5-8-27-14-29-22/h1-2,5,8-14,17,26H,3-4,6-7H2,(H2,25,28)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis				Bioorg Med Chem Lett 22: 4044-8 (2012) Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4
					More data for this Ligand-Target Pair