null

SMILES: Fc1ccc(cc1)S(=O)(=O)Cc1cc(nc(n1)-c1ccccn1)N1CCOCC1

InChI Key: InChIKey=JAUIOJAQQTUDNL-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50384261   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50384261 (CHEMBL2030439) Show SMILES Fc1ccc(cc1)S(=O)(=O)Cc1cc(nc(n1)-c1ccccn1)N1CCOCC1 Show InChI InChI=1S/C20H19FN4O3S/c21-15-4-6-17(7-5-15)29(26,27)14-16-13-19(25-9-11-28-12-10-25)24-20(23-16)18-3-1-2-8-22-18/h1-8,13H,9-12,14H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant FLAG-tagged mTOR kinase expressed in HEK293 cells using Biotin-Ahx-Lys-Lys-Ala-Asn-Gln-Val-Phe-Leu-Gly-Phe-Thr-Tyr-Val-Ala-...				Bioorg Med Chem Lett 22: 4163-8 (2012) Article DOI: 10.1016/j.bmcl.2012.04.036 BindingDB Entry DOI: 10.7270/Q2N017KD
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50384261 (CHEMBL2030439) Show SMILES Fc1ccc(cc1)S(=O)(=O)Cc1cc(nc(n1)-c1ccccn1)N1CCOCC1 Show InChI InChI=1S/C20H19FN4O3S/c21-15-4-6-17(7-5-15)29(26,27)14-16-13-19(25-9-11-28-12-10-25)24-20(23-16)18-3-1-2-8-22-18/h1-8,13H,9-12,14H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human recombinant PI3Kalpha expressed in baculovirus system using PI(4,5)P2 as substrate after 20 mins				Bioorg Med Chem Lett 22: 4163-8 (2012) Article DOI: 10.1016/j.bmcl.2012.04.036 BindingDB Entry DOI: 10.7270/Q2N017KD
					More data for this Ligand-Target Pair