BDBM50384338 CHEMBL2031007

SMILES: CCCN(CCC)c1nccc(n1)-c1ccc(cc1C(=O)N1CCc2ccccc2C1)C(=O)NS(=O)(=O)c1ccc2ccccc2c1

InChI Key: InChIKey=NQDFVCRVTDLQIJ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50384338   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM50384338 (CHEMBL2031007) Show SMILES CCCN(CCC)c1nccc(n1)-c1ccc(cc1C(=O)N1CCc2ccccc2C1)C(=O)NS(=O)(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C37H37N5O4S/c1-3-20-41(21-4-2)37-38-19-17-34(39-37)32-16-14-29(24-33(32)36(44)42-22-18-27-10-6-8-12-30(27)25-42)35(43)40-47(45,46)31-15-13-26-9-5-7-11-28(26)23-31/h5-17,19,23-24H,3-4,18,20-22,25H2,1-2H3,(H,40,43)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research Curated by ChEMBL					Assay Description Inhibition of biotin-labelled Bcl-xL using [FAM]-IWIAQELRRIGDEFNAYY-NH2 as substrate after 60 mins by FRET analysis				Bioorg Med Chem Lett 22: 3951-6 (2012) Article DOI: 10.1016/j.bmcl.2012.04.106 BindingDB Entry DOI: 10.7270/Q2416Z2Z
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50384338 (CHEMBL2031007) Show SMILES CCCN(CCC)c1nccc(n1)-c1ccc(cc1C(=O)N1CCc2ccccc2C1)C(=O)NS(=O)(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C37H37N5O4S/c1-3-20-41(21-4-2)37-38-19-17-34(39-37)32-16-14-29(24-33(32)36(44)42-22-18-27-10-6-8-12-30(27)25-42)35(43)40-47(45,46)31-15-13-26-9-5-7-11-28(26)23-31/h5-17,19,23-24H,3-4,18,20-22,25H2,1-2H3,(H,40,43)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research Curated by ChEMBL					Assay Description Inhibition of GST-tagged Bcl2 using [FAM]-IWIAQELRRIGDEFNAYY-NH2 as substrate after 60 mins by fluorescence polarization assay				Bioorg Med Chem Lett 22: 3951-6 (2012) Article DOI: 10.1016/j.bmcl.2012.04.106 BindingDB Entry DOI: 10.7270/Q2416Z2Z
					More data for this Ligand-Target Pair