BDBM50384554 CHEMBL2036451

SMILES: Clc1ccc(cc1)-c1ccc(o1)-c1noc(=O)n1-c1ccc(cc1)N1CCNCC1

InChI Key: InChIKey=NWWGWXIYJUQJCJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50384554   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50384554 (CHEMBL2036451) Show SMILES Clc1ccc(cc1)-c1ccc(o1)-c1noc(=O)n1-c1ccc(cc1)N1CCNCC1 Show InChI InChI=1S/C22H19ClN4O3/c23-16-3-1-15(2-4-16)19-9-10-20(29-19)21-25-30-22(28)27(21)18-7-5-17(6-8-18)26-13-11-24-12-14-26/h1-10,24H,11-14H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of MK2 using 5TAMRA-KKLNRTLSVA-COOH as substrate incubated for 30 mins prior to substrate addition measured after 30 mins by immobilized m...				ACS Med Chem Lett 3: 100-105 (2012) Article DOI: 10.1021/ml200238g BindingDB Entry DOI: 10.7270/Q2K0759N
					More data for this Ligand-Target Pair