BDBM50384575 CHEMBL2036460

SMILES: Clc1ccc(cc1)-c1ccc(o1)C1=NOC(N1c1ccc(cc1)N1CCNCC1)c1ccncn1

InChI Key: InChIKey=DZJUCPPEXXLYJS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50384575   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50384575 (CHEMBL2036460) Show SMILES Clc1ccc(cc1)-c1ccc(o1)C1=NOC(N1c1ccc(cc1)N1CCNCC1)c1ccncn1 |t:14| Show InChI InChI=1S/C26H23ClN6O2/c27-19-3-1-18(2-4-19)23-9-10-24(34-23)25-31-35-26(22-11-12-29-17-30-22)33(25)21-7-5-20(6-8-21)32-15-13-28-14-16-32/h1-12,17,26,28H,13-16H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of MK2 using 5TAMRA-KKLNRTLSVA-COOH as substrate incubated for 30 mins prior to substrate addition measured after 30 mins by immobilized m...				ACS Med Chem Lett 3: 100-105 (2012) Article DOI: 10.1021/ml200238g BindingDB Entry DOI: 10.7270/Q2K0759N
					More data for this Ligand-Target Pair