BDBM50384712 CHEMBL2037198

SMILES: Fc1ccc2NC(=O)\C(=C\c3ccc(o3)-c3cccc(c3)C(=O)NC3CC3)c2c1

InChI Key: InChIKey=AZCMGIZOUJMZKI-XDHOZWIPSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50384712   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50384712 (CHEMBL2037198) Show SMILES Fc1ccc2NC(=O)\C(=C\c3ccc(o3)-c3cccc(c3)C(=O)NC3CC3)c2c1 Show InChI InChI=1S/C23H17FN2O3/c24-15-4-8-20-18(11-15)19(23(28)26-20)12-17-7-9-21(29-17)13-2-1-3-14(10-13)22(27)25-16-5-6-16/h1-4,7-12,16H,5-6H2,(H,25,27)(H,26,28)/b19-12+	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	109	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate by radiometric assay				ACS Med Chem Lett 3: 135-139 (2012) Article DOI: 10.1021/ml200259q BindingDB Entry DOI: 10.7270/Q2X92CBW
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50384712 (CHEMBL2037198) Show SMILES Fc1ccc2NC(=O)\C(=C\c3ccc(o3)-c3cccc(c3)C(=O)NC3CC3)c2c1 Show InChI InChI=1S/C23H17FN2O3/c24-15-4-8-20-18(11-15)19(23(28)26-20)12-17-7-9-21(29-17)13-2-1-3-14(10-13)22(27)25-16-5-6-16/h1-4,7-12,16H,5-6H2,(H,25,27)(H,26,28)/b19-12+	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	506	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assay				ACS Med Chem Lett 3: 135-139 (2012) Article DOI: 10.1021/ml200259q BindingDB Entry DOI: 10.7270/Q2X92CBW
					More data for this Ligand-Target Pair