BDBM50384719 CHEMBL2037206

SMILES: CCC(=C1C(=O)Nc2ccc(Cl)cc12)c1ccc(o1)-c1cccc(c1)C(=O)N1CCCN(C)CC1

InChI Key: InChIKey=BZJVKWLOCYVMBE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50384719   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50384719 (CHEMBL2037206) Show SMILES CCC(=C1C(=O)Nc2ccc(Cl)cc12)c1ccc(o1)-c1cccc(c1)C(=O)N1CCCN(C)CC1 Show InChI InChI=1S/C28H28ClN3O3/c1-3-21(26-22-17-20(29)8-9-23(22)30-27(26)33)25-11-10-24(35-25)18-6-4-7-19(16-18)28(34)32-13-5-12-31(2)14-15-32/h4,6-11,16-17H,3,5,12-15H2,1-2H3,(H,30,33)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	131	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assay				ACS Med Chem Lett 3: 135-139 (2012) Article DOI: 10.1021/ml200259q BindingDB Entry DOI: 10.7270/Q2X92CBW
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50384719 (CHEMBL2037206) Show SMILES CCC(=C1C(=O)Nc2ccc(Cl)cc12)c1ccc(o1)-c1cccc(c1)C(=O)N1CCCN(C)CC1 Show InChI InChI=1S/C28H28ClN3O3/c1-3-21(26-22-17-20(29)8-9-23(22)30-27(26)33)25-11-10-24(35-25)18-6-4-7-19(16-18)28(34)32-13-5-12-31(2)14-15-32/h4,6-11,16-17H,3,5,12-15H2,1-2H3,(H,30,33)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate by radiometric assay				ACS Med Chem Lett 3: 135-139 (2012) Article DOI: 10.1021/ml200259q BindingDB Entry DOI: 10.7270/Q2X92CBW
					More data for this Ligand-Target Pair