BDBM50384765 CHEMBL2037363

SMILES: CCCCn1sc(=O)n(CCCC)c1=O

InChI Key: InChIKey=WXPYTMMRDMUNOR-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50384765   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Regulator of G-protein signaling 4 (RGS4) (Homo sapiens (Human))	BDBM50384765 (CHEMBL2037363) Show SMILES CCCCn1sc(=O)n(CCCC)c1=O Show InChI InChI=1S/C10H18N2O2S/c1-3-5-7-11-9(13)12(8-6-4-2)15-10(11)14/h3-8H2,1-2H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of RGS4 interaction with Galpha0 protein by flow cytometry protein interaction assay				ACS Med Chem Lett 3: 146-150 (2012) Article DOI: 10.1021/ml200263y BindingDB Entry DOI: 10.7270/Q2NS0VXW
					More data for this Ligand-Target Pair
Sortase A (SrtA) (Staphylococcus aureus)	BDBM50384765 (CHEMBL2037363) Show SMILES CCCCn1sc(=O)n(CCCC)c1=O Show InChI InChI=1S/C10H18N2O2S/c1-3-5-7-11-9(13)12(8-6-4-2)15-10(11)14/h3-8H2,1-2H3	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Guizhou University Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) assessed as reduction in IsdA (64 to 323 residues)...				J Med Chem 63: 8442-8457 (2020)
					More data for this Ligand-Target Pair
Sortase A (SrtA) (Staphylococcus aureus)	BDBM50384765 (CHEMBL2037363) Show SMILES CCCCn1sc(=O)n(CCCC)c1=O Show InChI InChI=1S/C10H18N2O2S/c1-3-5-7-11-9(13)12(8-6-4-2)15-10(11)14/h3-8H2,1-2H3	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.39E+4	n/a	n/a	n/a	n/a	n/a	n/a
Guizhou University Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...				J Med Chem 63: 8442-8457 (2020)
					More data for this Ligand-Target Pair
Regulator of G-protein signaling 8 (Homo sapiens (Human))	BDBM50384765 (CHEMBL2037363) Show SMILES CCCCn1sc(=O)n(CCCC)c1=O Show InChI InChI=1S/C10H18N2O2S/c1-3-5-7-11-9(13)12(8-6-4-2)15-10(11)14/h3-8H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.22E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of RGS8 interaction with Galpha0 protein by flow cytometry protein interaction assay				ACS Med Chem Lett 3: 146-150 (2012) Article DOI: 10.1021/ml200263y BindingDB Entry DOI: 10.7270/Q2NS0VXW
					More data for this Ligand-Target Pair