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SMILES: Cn1cnc2c(-c3ccc(cc3)C3(N)CCC3)c(ccc12)-c1ccccc1

InChI Key: InChIKey=KQBSFOHZTGMBMA-UHFFFAOYSA-N

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50384844   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
RAC-alpha serine/threonine-protein kinase


(Homo sapiens (Human))		BDBM50384844
PNG
(CHEMBL2035037)
Show SMILES Cn1cnc2c(-c3ccc(cc3)C3(N)CCC3)c(ccc12)-c1ccccc1
Show InChI InChI=1S/C24H23N3/c1-27-16-26-23-21(27)13-12-20(17-6-3-2-4-7-17)22(23)18-8-10-19(11-9-18)24(25)14-5-15-24/h2-4,6-13,16H,5,14-15,25H2,1H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.80E+3n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of AKT1

J Med Chem 55: 1261-73 (2012)


Article DOI: 10.1021/jm201394e
BindingDB Entry DOI: 10.7270/Q2H41SGT
More data for this
Ligand-Target Pair