BindingDB logo
myBDB logout

null

SMILES: NC1(CCC1)c1ccc(cc1)-c1c(ccn2ncnc12)-c1ccccc1

InChI Key: InChIKey=SVMKTIMVFDYDLB-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50384846   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
RAC-alpha serine/threonine-protein kinase


(Homo sapiens (Human))		BDBM50384846
PNG
(CHEMBL2035035)
Show SMILES NC1(CCC1)c1ccc(cc1)-c1c(ccn2ncnc12)-c1ccccc1
Show InChI InChI=1S/C22H20N4/c23-22(12-4-13-22)18-9-7-17(8-10-18)20-19(16-5-2-1-3-6-16)11-14-26-21(20)24-15-25-26/h1-3,5-11,14-15H,4,12-13,23H2
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.67E+3n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of AKT1

J Med Chem 55: 1261-73 (2012)


Article DOI: 10.1021/jm201394e
BindingDB Entry DOI: 10.7270/Q2H41SGT
More data for this
Ligand-Target Pair