BDBM50385003 CHEMBL2035378

SMILES: Nc1ccccc1NC(=O)CCCNCC(=O)Nc1cccc(Cl)c1

InChI Key: InChIKey=QIFYMWVNUDQGPS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50385003   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50385003 (CHEMBL2035378) Show SMILES Nc1ccccc1NC(=O)CCCNCC(=O)Nc1cccc(Cl)c1 Show InChI InChI=1S/C18H21ClN4O2/c19-13-5-3-6-14(11-13)22-18(25)12-21-10-4-9-17(24)23-16-8-2-1-7-15(16)20/h1-3,5-8,11,21H,4,9-10,12,20H2,(H,22,25)(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Guru Ghasidas University Curated by ChEMBL					Assay Description Inhibition of HDAC1 using Fluor de Lys as substrate by fluorescence analysis				Eur J Med Chem 53: 390-7 (2012) Article DOI: 10.1016/j.ejmech.2012.03.058 BindingDB Entry DOI: 10.7270/Q25M66QJ
					More data for this Ligand-Target Pair