BDBM50385010 CHEMBL2035385

SMILES: Nc1ccccc1NC(=O)CCCNCC(=O)Nc1cc(Cl)ccc1Cl

InChI Key: InChIKey=VFADSFSWDHLMPB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50385010   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50385010 (CHEMBL2035385) Show SMILES Nc1ccccc1NC(=O)CCCNCC(=O)Nc1cc(Cl)ccc1Cl Show InChI InChI=1S/C18H20Cl2N4O2/c19-12-7-8-13(20)16(10-12)24-18(26)11-22-9-3-6-17(25)23-15-5-2-1-4-14(15)21/h1-2,4-5,7-8,10,22H,3,6,9,11,21H2,(H,23,25)(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Guru Ghasidas University Curated by ChEMBL					Assay Description Inhibition of HDAC1 using Fluor de Lys as substrate by fluorescence analysis				Eur J Med Chem 53: 390-7 (2012) Article DOI: 10.1016/j.ejmech.2012.03.058 BindingDB Entry DOI: 10.7270/Q25M66QJ
					More data for this Ligand-Target Pair