BDBM50385013 CHEMBL2035388

SMILES: Nc1ccccc1NC(=O)c1ccc(NCC(=O)Nc2ccccc2Cl)cc1

InChI Key: InChIKey=BILLVLCABRVYRR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50385013   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50385013 (CHEMBL2035388) Show SMILES Nc1ccccc1NC(=O)c1ccc(NCC(=O)Nc2ccccc2Cl)cc1 Show InChI InChI=1S/C21H19ClN4O2/c22-16-5-1-3-7-18(16)25-20(27)13-24-15-11-9-14(10-12-15)21(28)26-19-8-4-2-6-17(19)23/h1-12,24H,13,23H2,(H,25,27)(H,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Guru Ghasidas University Curated by ChEMBL					Assay Description Inhibition of HDAC1 using Fluor de Lys as substrate by fluorescence analysis				Eur J Med Chem 53: 390-7 (2012) Article DOI: 10.1016/j.ejmech.2012.03.058 BindingDB Entry DOI: 10.7270/Q25M66QJ
					More data for this Ligand-Target Pair