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SMILES: COc1ccc2c(c1)oc1c2nc([nH]c1=O)-c1ccccc1Cl

InChI Key: InChIKey=VXUOYQBXMFJHDU-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50385066   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50385066 (CHEMBL2035615) Show SMILES COc1ccc2c(c1)oc1c2nc([nH]c1=O)-c1ccccc1Cl Show InChI InChI=1S/C17H11ClN2O3/c1-22-9-6-7-11-13(8-9)23-15-14(11)19-16(20-17(15)21)10-4-2-3-5-12(10)18/h2-8H,1H3,(H,19,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Exelixis Curated by ChEMBL					Assay Description Inhibition of N-terminal His-tagged human PIM1 expressed in Escherichia coli using AKRRRLSA as substrate after 1 to 2 hrs by luciferasse-luciferin-co...				Bioorg Med Chem Lett 22: 3732-8 (2012) Article DOI: 10.1016/j.bmcl.2012.04.025 BindingDB Entry DOI: 10.7270/Q2X34ZHV
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50385066 (CHEMBL2035615) Show SMILES COc1ccc2c(c1)oc1c2nc([nH]c1=O)-c1ccccc1Cl Show InChI InChI=1S/C17H11ClN2O3/c1-22-9-6-7-11-13(8-9)23-15-14(11)19-16(20-17(15)21)10-4-2-3-5-12(10)18/h2-8H,1H3,(H,19,20,21)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Exelixis Curated by ChEMBL					Assay Description Inhibition of N-terminal His-tagged human PIM3 expressed in Escherichia coli using AKRRRLSA as substrate after 1 to 2 hrs by luciferasse-luciferin-co...				Bioorg Med Chem Lett 22: 3732-8 (2012) Article DOI: 10.1016/j.bmcl.2012.04.025 BindingDB Entry DOI: 10.7270/Q2X34ZHV
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50385066 (CHEMBL2035615) Show SMILES COc1ccc2c(c1)oc1c2nc([nH]c1=O)-c1ccccc1Cl Show InChI InChI=1S/C17H11ClN2O3/c1-22-9-6-7-11-13(8-9)23-15-14(11)19-16(20-17(15)21)10-4-2-3-5-12(10)18/h2-8H,1H3,(H,19,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Exelixis Curated by ChEMBL					Assay Description Inhibition of N-terminal His-tagged human PIM2 expressed in Escherichia coli using AKRRRLSA as substrate after 1 to 2 hrs by luciferasse-luciferin-co...				Bioorg Med Chem Lett 22: 3732-8 (2012) Article DOI: 10.1016/j.bmcl.2012.04.025 BindingDB Entry DOI: 10.7270/Q2X34ZHV
					More data for this Ligand-Target Pair